{"id":653,"date":"2017-11-02T12:59:17","date_gmt":"2017-11-02T09:59:17","guid":{"rendered":"http:\/\/microbio.bas.bg\/wordpress\/?page_id=653"},"modified":"2020-11-25T17:12:18","modified_gmt":"2020-11-25T14:12:18","slug":"laboratoriya-po-genna-ekspresiya","status":"publish","type":"page","link":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/struktura\/nauchni-zvena-2\/departament-obshta-mikrobiologiya\/584-2\/laboratoriya-po-genna-ekspresiya\/","title":{"rendered":"\u041b\u0410\u0411\u041e\u0420\u0410\u0422\u041e\u0420\u0418\u042f \u041f\u041e &#8222;\u0413\u0415\u041d\u041d\u0410 \u0415\u041a\u0421\u041f\u0420\u0415\u0421\u0418\u042f\u201d"},"content":{"rendered":"<p class=\"clear-margins\"><span style=\"font-family: arial, helvetica, sans-serif; font-size: 14pt;\">\u0420\u044a\u043a\u043e\u0432\u043e\u0434\u0438\u0442\u0435\u043b: \u041f\u0440\u043e\u0444. \u0434-\u0440 \u041f\u0435\u043d\u043a\u0430 \u041f\u0435\u0442\u0440\u043e\u0432\u0430<\/span><\/p>\n<p class=\"clear-margins\"><span style=\"font-family: arial, helvetica, sans-serif;\">\u0422e\u043b.: + 359 2 979 31 79<\/span><\/p>\n<p class=\"clear-margins\"><span style=\"font-family: arial, helvetica, sans-serif;\">E-mail: <a href=\"mailto:pepipetrova@yahoo.com\">pepipetrova@yahoo.com<\/a><\/span><\/p>\n<p>&nbsp;<\/p>\n<table style=\"width: 100%; height: 60px; background-color: #f0f1f5;\">\n<tbody>\n<tr>\n<td style=\"text-align: center;\"><span style=\"font-size: 18pt; font-family: arial, helvetica, sans-serif;\"><strong>\u0421\u042a\u0421\u0422\u0410\u0412:<\/strong><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"font-family: arial, helvetica, sans-serif;\"><\/span><\/p>\n<p>&nbsp;<\/p>\n<table style=\"background-color: #f0f1f5; height: 60px;\" width=\"100%\">\n<tbody>\n<tr>\n<td style=\"text-align: center;\"><span style=\"font-size: 18pt; font-family: arial, helvetica, sans-serif;\"><strong>\u0418\u0417\u0421\u041b\u0415\u0414\u041e\u0412\u0410\u0422\u0415\u041b\u0421\u041a\u0410 \u0414\u0415\u0419\u041d\u041e\u0421\u0422 \u0412 \u041e\u0411\u041b\u0410\u0421\u0422\u0422\u0410 \u041d\u0410: \u00a0<\/strong><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\"><span style=\"font-family: arial, helvetica, sans-serif;\">\u0412 \u043b\u0430\u0431\u043e\u0440\u0430\u0442\u043e\u0440\u0438\u044f\u0442\u0430 \u0441\u0435 \u0438\u0437\u0432\u044a\u0440\u0448\u0432\u0430\u0442 \u0438\u0437\u0441\u043b\u0435\u0434\u0432\u0430\u043d\u0438\u044f \u0432 \u043e\u0431\u043b\u0430\u0441\u0442\u0442\u0430 \u043d\u0430 \u0433\u0435\u043d\u043e\u043c\u0438\u043a\u0430\u0442\u0430, \u0442\u0440\u0430\u043d\u0441\u043a\u0440\u0438\u043f\u0442\u043e\u043c\u0438\u043a\u0430\u0442\u0430 \u0438 \u043f\u0440\u043e\u0442\u0435\u043e\u043c\u0438\u043a\u0430\u0442\u0430 \u043d\u0430 \u0440\u0430\u0437\u043b\u0438\u0447\u043d\u0438 \u043c\u043e\u0434\u0435\u043b\u043d\u0438 \u0441\u0438\u0441\u0442\u0435\u043c\u0438 \u043f\u0440\u043e\u043a\u0430\u0440\u0438\u043e\u0442\u0438 (\u043c\u043b\u0435\u0447\u043d\u043e\u043a\u0438\u0441\u0435\u043b\u0438 \u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0438 (\u041c\u041a\u0411), <em>E. coli<\/em>, <em>Bacillus<\/em>) \u0438 \u0435\u0443\u043a\u0430\u0440\u0438\u043e\u0442\u0438 <em>(<\/em><em>Ogataea polymorpha<\/em>, <em>Pichia pastoris<\/em>). \u0418\u0437\u0443\u0447\u0430\u0432\u0430 \u0441\u0435 \u0440\u0435\u0433\u0443\u043b\u0430\u0446\u0438\u044f\u0442\u0430 \u043d\u0430 \u0433\u0435\u043d\u043d\u0430\u0442\u0430 \u0435\u043a\u0441\u043f\u0440\u0435\u0441\u0438\u044f \u043d\u0430 \u043d\u043e\u0432\u0438 \u0433\u043b\u0438\u043a\u043e\u0437\u0438\u0434-\u0445\u0438\u0434\u0440\u043e\u043b\u0430\u0437\u043d\u0438 \u0435\u043d\u0437\u0438\u043c\u0438 (\u0430\u043c\u0438\u043b\u0430\u0437\u0438, \u0444\u0440\u0443\u043a\u0442\u0430\u043d-\u03b2-\u0444\u0440\u0443\u043a\u0442\u043e\u0437\u0438\u0434\u0430\u0437\u0438, \u03b2-\u0433\u0430\u043b\u0430\u043a\u0442\u043e\u0437\u0438\u0434\u0430\u0437\u0438), \u0432\u043e\u0434\u0435\u0449\u0438 \u0434\u043e \u0441\u0438\u043d\u0442\u0435\u0437 \u0438\u043b\u0438 \u0443\u0441\u0432\u043e\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u043f\u0440\u0435\u0431\u0438\u043e\u0442\u0438\u0447\u043d\u0438 \u0432\u044a\u0433\u043b\u0435\u0445\u0438\u0434\u0440\u0430\u0442\u0438 (\u0433\u0430\u043b\u0430\u043a\u0442\u043e\u043e\u043b\u0438\u0433\u043e\u0437\u0430\u0445\u0430\u0440\u0438\u0434\u0438, \u0444\u0440\u0443\u043a\u0442\u043e\u043e\u043b\u0438\u0433\u043e\u0437\u0430\u0445\u0430\u0440\u0438\u0434\u0438, \u0438\u043d\u0443\u043b\u0438\u043d) \u043e\u0442 \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u0447\u043d\u0438 \u0449\u0430\u043c\u043e\u0432\u0435 \u041c\u041a\u0411. \u0420\u0430\u0437\u0440\u0430\u0431\u043e\u0442\u0432\u0430\u0442 \u0441\u0435 \u043d\u043e\u0432\u0438 \u0441\u0438\u043d\u0431\u0438\u043e\u0442\u0438\u0447\u043d\u0438 \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u0438 \u0441 \u043f\u0440\u0438\u043b\u043e\u0436\u0435\u043d\u0438\u0435 \u0432 \u0445\u0440\u0430\u043d\u0438\u0442\u0435\u043b\u043d\u043e-\u0432\u043a\u0443\u0441\u043e\u0432\u0430\u0442\u0430 \u043f\u0440\u043e\u043c\u0438\u0448\u043b\u0435\u043d\u043e\u0441\u0442 \u0438 \u0432\u0435\u0442\u0435\u0440\u0438\u043d\u0430\u0440\u043d\u0430\u0442\u0430 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0430.<\/span><\/p>\n<p>&nbsp;<\/p>\n<table style=\"background-color: #f0f1f5; width: 100%; height: 60px;\">\n<tbody>\n<tr>\n<td style=\"text-align: center;\"><span style=\"font-size: 18pt; font-family: arial, helvetica, sans-serif;\"><strong>\u041f\u0420\u041e\u0415\u041a\u0422\u0418:<\/strong><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"font-size: 14pt; font-family: arial, helvetica, sans-serif;\"><strong>\u0422\u0435\u043a\u0443\u0449\u0438:<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"font-family: arial, helvetica, sans-serif;\">2015\u20132018 \u0418\u0437\u043e\u043b\u0438\u0440\u0430\u043d\u0435, \u0438\u0434\u0435\u043d\u0442\u0438\u0444\u0438\u043a\u0430\u0446\u0438\u044f \u0438 \u0445\u0430\u0440\u0430\u043a\u0442\u0435\u0440\u0438\u0437\u0438\u0440\u0430\u043d\u0435 \u043d\u0430 \u0449\u0430\u043c\u043e\u0432\u0435 <em>Lactobacillus<\/em>, \u0438\u0437\u043e\u043b\u0438\u0440\u0430\u043d\u0438 \u043e\u0442 \u0431\u044a\u043b\u0433\u0430\u0440\u0441\u043a\u0438 \u0434\u043e\u043c\u0430\u0448\u043d\u0438 \u0444\u0435\u0440\u043c\u0435\u043d\u0442\u0438\u0440\u0430\u043b\u0438 \u043c\u043b\u0435\u0447\u043d\u0438 \u043f\u0440\u043e\u0434\u0443\u043a\u0442\u0438 &#8211; \u0434\u043e\u0433\u043e\u0432\u043e\u0440 \u0441 Bright Dairy Foods &amp; Co. Ltd., \u041a\u0438\u0442\u0430\u0439.<\/span><\/li>\n<li><span style=\"font-family: arial, helvetica, sans-serif;\">2015-2017 \u041c\u043e\u0434\u0435\u0440\u043d\u0438 \u043c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u0438 \u043f\u043e\u0434\u0445\u043e\u0434\u0438 \u0437\u0430 \u0444\u0443\u043d\u043a\u0446\u0438\u043e\u043d\u0430\u043b\u043d\u043e \u0445\u0430\u0440\u0430\u043a\u0442\u0435\u0440\u0438\u0437\u0438\u0440\u0430\u043d\u0435 \u043d\u0430 \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u0447\u043d\u0438 \u0441\u0432\u043e\u0439\u0441\u0442\u0432\u0430 \u0438 \u0438\u0437\u0441\u043b\u0435\u0434\u0432\u0430\u043d\u0435 \u043d\u0430 \u0442\u0435\u0445\u043d\u043e\u043b\u043e\u0433\u0438\u0447\u043d\u0438 \u0445\u0430\u0440\u0430\u043a\u0442\u0435\u0440\u0438\u0441\u0442\u0438\u043a\u0438 \u043d\u0430 \u0430\u043c\u0438\u043b\u043e\u043b\u0438\u0442\u0438\u0447\u043d\u0438 \u043c\u043b\u0435\u0447\u043d\u043e-\u043a\u0438\u0441\u0435\u043b\u0438 \u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0438 \u043e\u0442 \u0431\u044a\u043b\u0433\u0430\u0440\u0441\u043a\u0438 \u0444\u0435\u0440\u043c\u0435\u043d\u0442\u0430\u0446\u0438\u043e\u043d\u043d\u0438 \u043f\u0440\u043e\u0434\u0443\u043a\u0442\u0438, \u0424\u041d\u0418.<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><span style=\"font-size: 14pt; font-family: arial, helvetica, sans-serif;\"><strong>\u041f\u0440\u0438\u043a\u043b\u044e\u0447\u0435\u043d\u0438 \u043f\u0440\u0435\u0437 \u043f\u043e\u0441\u043b\u0435\u0434\u043d\u0438\u0442\u0435 5 \u0433\u043e\u0434\u0438\u043d\u0438:<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"font-family: arial, helvetica, sans-serif;\">2012-2015 \u0410\u043c\u0438\u043b\u043e\u043b\u0438\u0442\u0438\u0447\u043d\u0438 \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u0446\u0438 \u0441 \u043f\u0440\u0438\u043b\u043e\u0436\u0435\u043d\u0438\u0435 \u0432 \u0445\u0440\u0430\u043d\u0438\u0442\u0435\u043b\u043d\u043e-\u0432\u043a\u0443\u0441\u043e\u0432\u0430\u0442\u0430 \u043f\u0440\u043e\u043c\u0438\u0448\u043b\u0435\u043d\u043e\u0441\u0442, \u0414\u041c\u0423 03\/45, \u0424\u041d\u0418.\u00a0<\/span><\/li>\n<li><span style=\"font-family: arial, helvetica, sans-serif;\">2009-2013 \u041d\u043e\u0432\u0438 \u043f\u043e\u043b\u0438\u0437\u0430\u0445\u0430\u0440\u0438\u0434-\u043c\u043e\u0434\u0438\u0444\u0438\u0446\u0438\u0440\u0430\u0449\u0438 \u0435\u043d\u0437\u0438\u043c\u0438, \u043e\u043f\u0442\u0438\u043c\u0438\u0437\u0438\u0440\u0430\u0449\u0438 \u043f\u043e\u0442\u0435\u043d\u0446\u0438\u0430\u043b\u0430 \u043d\u0430 \u0445\u0438\u0434\u0440\u043e\u043a\u043e\u043b\u043e\u0438\u0434\u0438\u0442\u0435 \u0437\u0430 \u043f\u0440\u0438\u043b\u043e\u0436\u0435\u043d\u0438\u0435 \u0432 \u0445\u0440\u0430\u043d\u0438\u0442\u0435 \u0438 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0430\u0442\u0430 \u201ePolyModE\u201d, 7\u0420\u041f \u043d\u0430 \u0415\u0421, \u2116222628 \u0438 \u0414\u0422\u041a 02\/09 (2010-2015), \u0424\u041d\u0418.<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<table style=\"background-color: #f0f1f5; width: 100%; height: 60px;\">\n<tbody>\n<tr>\n<td style=\"text-align: center;\"><span style=\"font-size: 18pt; font-family: arial, helvetica, sans-serif;\"><strong>\u041f\u0423\u0411\u041b\u0418\u041a\u0410\u0426\u0418\u0418:<\/strong><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul>\n<li><span style=\"font-family: arial, helvetica, sans-serif;\">Petrova P., Velikova P., Popova L., Petrov K. Direct conversion of chicory flour into L(+)-lactic acid by the highly effective inulinase producer Lactobacillus paracasei DSM 23505. Bioresource Technology 186, 329-333, Elsevier, 2015, ISSN: 0960-8524, DOI: 10.1016\/j.biortech.2015.03.077<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"font-family: arial, helvetica, sans-serif;\">Velikova P., Stoyanov A., Blagoeva G., Popova L., Petrov K., Gotcheva V., Angelov A., Petrova P. Starch utilization routes in lactic acid bacteria: new insight by gene expression assay. Starch-Starke 68, 953-960, Wiley-VCH Verlag GmbH &amp; Co, 2016, ISSN: 1521-379X, DOI: 10.1002\/star.201600023<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"font-family: arial, helvetica, sans-serif;\">Velikova P., Petrov K., Petrova P. The cell wall anchored \u03b2-fructosidases of Lactobacillus paracasei: overproduction, purification, and gene expression control. Process Biochemistry, 52, 53-62, Elsevier, 2017, ISSN: 1359-5113, DOI:10.1016\/j.procbio.2016.10.010.<\/span><\/li>\n<\/ul>\n<ul>\n<li><span style=\"font-family: arial, helvetica, sans-serif;\">Petrov K., Popova L., Petrova P. High lactic acid and fructose production via Mn2+ mediated conversion of inulin by Lactobacillus paracasei. Applied Microbiology and Biotechnology 101, 4433-4445, Springer Verlag, 2017, ISSN: 0175-7598, DOI: 10.1007\/s00253-017-8238-0.<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u0420\u044a\u043a\u043e\u0432\u043e\u0434\u0438\u0442\u0435\u043b: \u041f\u0440\u043e\u0444. \u0434-\u0440 \u041f\u0435\u043d\u043a\u0430 \u041f\u0435\u0442\u0440\u043e\u0432\u0430 \u0422e\u043b.: + 359 2 979 31 79 E-mail: pepipetrova@yahoo.com &nbsp; \u0421\u042a\u0421\u0422\u0410\u0412: &nbsp; \u0418\u0417\u0421\u041b\u0415\u0414\u041e\u0412\u0410\u0422\u0415\u041b\u0421\u041a\u0410 \u0414\u0415\u0419\u041d\u041e\u0421\u0422 \u0412 \u041e\u0411\u041b\u0410\u0421\u0422\u0422\u0410 \u041d\u0410: \u00a0 \u0412 \u043b\u0430\u0431\u043e\u0440\u0430\u0442\u043e\u0440\u0438\u044f\u0442\u0430 \u0441\u0435 \u0438\u0437\u0432\u044a\u0440\u0448\u0432\u0430\u0442 \u0438\u0437\u0441\u043b\u0435\u0434\u0432\u0430\u043d\u0438\u044f \u0432 \u043e\u0431\u043b\u0430\u0441\u0442\u0442\u0430 \u043d\u0430 \u0433\u0435\u043d\u043e\u043c\u0438\u043a\u0430\u0442\u0430, \u0442\u0440\u0430\u043d\u0441\u043a\u0440\u0438\u043f\u0442\u043e\u043c\u0438\u043a\u0430\u0442\u0430 \u0438 \u043f\u0440\u043e\u0442\u0435\u043e\u043c\u0438\u043a\u0430\u0442\u0430 \u043d\u0430 \u0440\u0430\u0437\u043b\u0438\u0447\u043d\u0438 \u043c\u043e\u0434\u0435\u043b\u043d\u0438 \u0441\u0438\u0441\u0442\u0435\u043c\u0438 \u043f\u0440\u043e\u043a\u0430\u0440\u0438\u043e\u0442\u0438 (\u043c\u043b\u0435\u0447\u043d\u043e\u043a\u0438\u0441\u0435\u043b\u0438 \u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0438 (\u041c\u041a\u0411), E. coli, Bacillus) \u0438 \u0435\u0443\u043a\u0430\u0440\u0438\u043e\u0442\u0438 (Ogataea polymorpha, Pichia pastoris). \u0418\u0437\u0443\u0447\u0430\u0432\u0430 \u0441\u0435 \u0440\u0435\u0433\u0443\u043b\u0430\u0446\u0438\u044f\u0442\u0430 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":584,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/pages\/653"}],"collection":[{"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/comments?post=653"}],"version-history":[{"count":6,"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/pages\/653\/revisions"}],"predecessor-version":[{"id":5046,"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/pages\/653\/revisions\/5046"}],"up":[{"embeddable":true,"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/pages\/584"}],"wp:attachment":[{"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/media?parent=653"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}