{"id":655,"date":"2017-11-02T13:04:35","date_gmt":"2017-11-02T10:04:35","guid":{"rendered":"http:\/\/microbio.bas.bg\/wordpress\/?page_id=655"},"modified":"2020-11-25T17:13:17","modified_gmt":"2020-11-25T14:13:17","slug":"gene-expression-laboratory","status":"publish","type":"page","link":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/en\/structure\/scientific-staff\/department-of-general-microbiology\/laboratory-of-microbial-genetics\/gene-expression-laboratory\/","title":{"rendered":"GENE EXPRESSION LABORATORY"},"content":{"rendered":"

Head: Prof. Penka Petrova,PhD<\/span><\/p>\n

Tel.: +359 2 979 31 79<\/span><\/p>\n

E-mail: pepipetrova@yahoo.com<\/a><\/span><\/p>\n

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STAFF:<\/span><\/strong><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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RESEARCH AREA: \u00a0<\/strong><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Genomics, Transcriptomics and Proteomics studies using prokaryotic and eukaryotic model systems: bacteria (E. coli, Lactobacillus, Lactococcus, Bacillus, Klebsiella) and yeasts (Ogataea polymorpha, Pichia pastoris). Studies on the gene activity regulation concerning novel polysaccharide-modifying enzymes (amylases, amylopullulanases, fructan-\u03b2-fructosidases, and \u03b2-galactosidases) related to prebiotics utilization or synthesis by Lactic acid bacteria. Development of novel synbiotic formulas with applications in food industry or veterinary medicine.<\/span><\/p>\n

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PROJECTS:<\/strong><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Ongoing:<\/strong><\/span><\/p>\n

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  • Isolation, identification and characterization of Lactobacillus strains, isolated from artisanal Bulgarian milk products, Contract with Bright Dairy Foods & Co. Ltd, China (2015-2018).<\/span><\/li>\n
  • Modern molecular approaches for functional and technological characterization of probiotic features of amylolytic lactic acid bacteria of Bulgarian fermentative products (2015-2017) funded by NSF, Republic of Bulgaria.<\/span><\/li>\n<\/ul>\n

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    Completed within the last 5 years:<\/strong><\/span><\/p>\n

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    • Amylolytic lactic acid bacteria with application in food industry (2012-2015) funded by NSF, Republic of Bulgaria.<\/span><\/li>\n
    • Novel Polyaccharide Modifying Enzymes to Optimize the Potential of Hydrocolloids for Food and Medical Applications, (2009-2013), Project \u2116: 222628 funded by the EU within the 7th\u00a0FP and (2010 \u2013 2015), funded by NSF, Republic of Bulgaria.<\/span><\/li>\n
    • Novel and recombinant cyclodextrin-glucanotransferases with industrial application (2010\u20132012), funded by NSF, Republic of Bulgaria.<\/span><\/li>\n
    • Lactic acid production by starch-hydrolyzing bacteria (2010 – 2012); European Social Fund, Grant BG 051PO001-3.3.04\/32.<\/span><\/li>\n<\/ul>\n

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      SELECTED PUBLICATIONS:<\/strong><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
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      • Petrova P., Velikova P., Popova L., Petrov K. Direct conversion of chicory flour into L(+)-lactic acid by the highly effective inulinase producer Lactobacillus paracasei DSM 23505. Bioresource Technology 186, 329-333, Elsevier, 2015, ISSN: 0960-8524, DOI: 10.1016\/j.biortech.2015.03.077<\/span><\/li>\n<\/ul>\n
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        • Velikova P., Stoyanov A., Blagoeva G., Popova L., Petrov K., Gotcheva V., Angelov A., Petrova P. Starch utilization routes in lactic acid bacteria: new insight by gene expression assay. Starch-Starke 68, 953-960, Wiley-VCH Verlag GmbH & Co, 2016, ISSN: 1521-379X, DOI: 10.1002\/star.201600023<\/span><\/li>\n<\/ul>\n
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          • Velikova P., Petrov K., Petrova P. The cell wall anchored \u03b2-fructosidases of Lactobacillus paracasei: overproduction, purification, and gene expression control. Process Biochemistry, 52, 53-62, Elsevier, 2017, ISSN: 1359-5113, DOI:10.1016\/j.procbio.2016.10.010.<\/span><\/li>\n<\/ul>\n
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            • Petrov K., Popova L., Petrova P. High lactic acid and fructose production via Mn2+ mediated conversion of inulin by Lactobacillus paracasei. Applied Microbiology and Biotechnology 101, 4433-4445, Springer Verlag, 2017, ISSN: 0175-7598, DOI: 10.1007\/s00253-017-8238-0.<\/span><\/li>\n<\/ul>\n

               <\/p>\n","protected":false},"excerpt":{"rendered":"

              Head: Prof. Penka Petrova,PhD Tel.: +359 2 979 31 79 E-mail: pepipetrova@yahoo.com   STAFF:   RESEARCH AREA: \u00a0 Genomics, Transcriptomics and Proteomics studies using prokaryotic and eukaryotic model systems: bacteria (E. coli, Lactobacillus, Lactococcus, Bacillus, Klebsiella) and yeasts (Ogataea polymorpha, Pichia pastoris). Studies on the gene activity regulation concerning novel polysaccharide-modifying enzymes (amylases, amylopullulanases, fructan-\u03b2-fructosidases, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":606,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/pages\/655"}],"collection":[{"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/comments?post=655"}],"version-history":[{"count":7,"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/pages\/655\/revisions"}],"predecessor-version":[{"id":5047,"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/pages\/655\/revisions\/5047"}],"up":[{"embeddable":true,"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/pages\/606"}],"wp:attachment":[{"href":"https:\/\/microbio.bas.bg\/wordpress\/index.php\/wp-json\/wp\/v2\/media?parent=655"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}