INFLAMMATION: FROM PROTECTIVE RESPONSE TO RECOVERY – ASSOC. PROF. PETYA DIMITROVA ON BLOOMBERG TV BULGARIA

INFLAMMATION: FROM PROTECTIVE RESPONSE TO RECOVERY – ASSOC. PROF. PETYA DIMITROVA ON BLOOMBERG TV BULGARIA
On November 5, 2026, Assoc. Prof. Dr. Petya Dimitrova from the "Stephan Angeloff" Institute of Microbiology at the Bulgarian Academy of Sciences was a guest on the "Futurism" show on Bloomberg TV Bulgaria. She presented the concept of resolution of inflammation embedded in the international network EU-RESOLVE. The network is funded under the COST programme (project CA24138) and supported by the Bulgarian National Science Fund through project KП-06-КОСТ/10.
During the conversation, Assoc. Prof. Dimitrova explained that inflammation is a necessary protective response, but for the body to recover, the inflammatory response must be terminated in a timely manner and followed by coordinated tissue resolution mechanisms. When these processes are disrupted, inflammation can become chronic and lead to tissue damage.
Assoc. Prof. Dimitrova presented research on specialized lipid mediators, including resolvins – molecules that participate in the natural termination of the inflammatory response. They create conditions for subsequent tissue restoration. One promising direction is the development of therapies that support the body's own mechanisms for resolving inflammation and repairing damaged tissues. To this end, scientists are studying molecules that mimic the action of natural signals directing recovery processes. Uncovering the numerous interconnected mechanisms involved in this process highlights new and unexpected aspects of resolution biology. One of the research areas focuses on determining pro-resolving lipid levels in cardiovascular diseases and diabetes, as well as whether these levels change under standard therapy. The goal for the future is to detect these molecules in serum, plasma, and other biological fluids to serve as indicators of whether the recovery process has begun.
"The immune response always begins with inflammation, which is a necessary reaction established as early as fetal development, but its final stages must also be resolved. Therefore, researchers are turning their attention to combinations of fatty acids that initiate a specific class of resolving molecules," Assoc. Prof. Dimitrova explained.

The full conversation can be viewed at: https://www.bloombergtv.bg/a/88-futurizam/166492-vazpalenieto-zashto-ponyakoga-zashtitata-na-organizma-ne-spira-navreme?route=88-futurizam