The Stephan Angeloff Institute of Microbiology
Member Of The International Institut Pasteur Network
Head: Prof. Svetla Danova, PhD
Tel.: +359 2 979 31 79
E-mail: stdanova@yahoo.com
CURRENT SCIENTIFIC FIELDS: |
The subjects of the study are lactic acid bacteria, streptomycetes, methylotrophic yeasts, ascomycetic and basidiomycetic yeasts and molds. The main approach in the research is the genetic analysis and regulation of genes in microorganisms. Molecular-taxonomic characterization of vaginal lactobacilli and MKB isolated from Bulgarian dairy products is performed. Their probiotic potential is characterized, molecular mechanisms of effectiveness and resistance to industrial stress are studied.
Enhancement of antibiotic productivity and activity of Streptomyces production strains. Cloning and sequencing of genes involved in spectinomycin biosynthesis in Streptomyces flavopersicus.
Construction of yeast strains of Ogataea polymorpha for the expression of heterologous genes.
Molecular, genetic and biochemical analyses of yeasts and molds (Aspergillus, Trametes, Penicillium, Cladosporium, etc.) capable of effectively degrading toxic aromatic and aliphatic compounds. Isolation of DNA sequences to study the biodegradation potential of microbial strains in industrially contaminated waters and soils. The possibility of biodegradation of monoaromatic and polyaromatic substances such as anthracene, naphthalene and phenanthrene from Trichosporon cutaneum strains, Aspergillus fumigatus, Penicillium commune, Alternaria maritima has been proven.
LABORATORIES: |
Acad. Georgi Bonchev street
blok. 26, Sofia, zip 1113
tel.: +359 2 979 31 57
+359 879 499 167
e-mail: micb@microbio.bas.bg
Cellular Biosystems Laboratory
Plovdiv, zip 4000
139, Ruski blvd.
Manager: soc. Prof. Dr. Vasil Georgiev
Metabolomica Laboratory
Plovdiv, zip 4000
139, Ruski blvd.
Manager: Prof. Dr. Milen Georgiev
Laboratory “Ecology of pathogenic bacteria”
Veliko Tarnovo, zip 5002
78 Nikola Gabrovski Str., floor. 4
Manager: Ch. Assistant Professor Dr. Zvezdimira Tsvetanova